RGS19_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: RGS19 , GAIP, GNAI3IP
Protein names and data: RGS19_HUMAN , Regulator of G-protein signaling 19; RGS19 , G-alpha-interacting protein; GAIP Lenght: 217 a.a.
Mass: 24636 Da
fasta formatted sequence
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Cellular location: Membrane; Lipid-anchor.
Tissue specificity: Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.

Database cross-references

UniProt: P49795
Ensembl: ENST00000332298
Ensembl: ENST00000395042
MIM: 605071
neXtProt: NX_P49795
Antibodypedia: P49795 (may not find the protein thus also not any antibody)
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