RIR1_HUMAN

Source: hRBCD ; ID: IPI00013871
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: RRM1 , RR1
Protein names and data: RIR1_HUMAN , Ribonucleoside-diphosphate reductase large subunit; 1.17.4.1 , Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit Lenght: 792 a.a.
Mass: 90070 Da
fasta formatted sequence
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Catalytic activity: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H(2)O = ribonucleoside diphosphate + thioredoxin.
Pathway: Genetic information processing; DNA replication.
Cellular location: Cytoplasm.

Genetic variants

Database cross-references

UniProt: P23921
Ensembl: ENST00000300738
MIM: 180410
neXtProt: NX_P23921
Antibodypedia: P23921 (may not find the protein thus also not any antibody)
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