Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: RRAS2 , TC21
Protein names and data: RRAS2_HUMAN , Ras-related protein R-Ras2 , Ras-like protein TC21; Teratocarcinoma oncogene; Flags: Precursor Lenght: 204 a.a.
Mass: 23400 Da
fasta formatted sequence

Function: It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
Tissue specificity: Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.

Genetic variants

Database cross-references

UniProt: P62070
Ensembl: ENST00000256196
Ensembl: ENST00000414023
Ensembl: ENST00000526063
Ensembl: ENST00000529237
Ensembl: ENST00000532814
Ensembl: ENST00000534746
Ensembl: ENST00000537760
Ensembl: ENST00000571727
Ensembl: ENST00000572201
Ensembl: ENST00000572397
Ensembl: ENST00000572894
Ensembl: ENST00000573870
Ensembl: ENST00000574530
MIM: 167000
MIM: 600098
neXtProt: NX_P62070
Antibodypedia: P62070 (may not find the protein thus also not any antibody)
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