S10AE_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: S100A14 , S100A15
Protein names and data: S10AE_HUMAN , Protein S100-A14 , S100 calcium-binding protein A14; S114 Lenght: 104 a.a.
Mass: 11662 Da
fasta formatted sequence
Function: Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
Cellular location: Cytoplasm.
Tissue specificity: Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.

Database cross-references

UniProt: Q9HCY8
Ensembl: ENST00000344616
Ensembl: ENST00000368701
Ensembl: ENST00000368702
Ensembl: ENST00000476873
MIM: 607986
neXtProt: NX_Q9HCY8
Antibodypedia: Q9HCY8 (may not find the protein thus also not any antibody)
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