S19A1_HUMAN

Source: hRBCD ; ID: IPI00299186
PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: SLC19A1 , FLOT1, RFC1
Protein names and data: S19A1_HUMAN , Folate transporter 1; FOLT , Intestinal folate carrier 1; IFC-1; Placental folate transporter; Reduced folate carrier protein; RFC; Solute carrier family 19 member 1 Lenght: 591 a.a.
Mass: 64868 Da
fasta formatted sequence

Function: Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.
Cellular location: Membrane; Multi-pass membrane protein.
Tissue specificity: Placenta, liver, and to a much smaller extent, in lung.

Genetic variants

Database cross-references

UniProt: P41440
Ensembl: ENST00000311124
Ensembl: ENST00000380010
Ensembl: ENST00000485649
MIM: 600424
neXtProt: NX_P41440
Antibodypedia: P41440 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.