Source: PM19886704
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: SLC29A1 , ENT1
Protein names and data: S29A1_HUMAN , Equilibrative nucleoside transporter 1 , Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1 Lenght: 456 a.a.
Mass: 50219 Da
fasta formatted sequence

Function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
Cellular location: Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells.
Tissue specificity: Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

Genetic variants

Database cross-references

UniProt: Q99808
Ensembl: ENST00000371708
Ensembl: ENST00000371713
Ensembl: ENST00000371724
Ensembl: ENST00000371731
Ensembl: ENST00000371740
Ensembl: ENST00000371755
Ensembl: ENST00000393841
Ensembl: ENST00000393844
Ensembl: ENST00000427851
MIM: 602193
neXtProt: NX_Q99808
Antibodypedia: Q99808 (may not find the protein thus also not any antibody)
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