Source: hRBCD ; ID: IPI00006865
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: SEC22B , SEC22L1
Protein names and data: SC22B_HUMAN , Vesicle-trafficking protein SEC22b , ER-Golgi SNARE of 24 kDa; ERS-24; ERS24; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1 Lenght: 215 a.a.
Mass: 24593 Da
fasta formatted sequence

Function: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
Cellular location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity). Endoplasmic reticulum- Golgi intermediate compartment membrane (By similarity). Golgi apparatus, cis-Golgi network membrane (By similarity). Golgi apparatus, trans-Golgi network membrane (By similarity). Melanosome. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Genetic variants

Database cross-references

UniProt: O75396
MIM: 604029
neXtProt: NX_O75396
Antibodypedia: O75396 (may not find the protein thus also not any antibody)
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