SEC13_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: SEC13 , D3S1231E, SEC13L1, SEC13R
Protein names and data: SEC13_HUMAN , Protein SEC13 homolog , SEC13-like protein 1; SEC13-related protein Lenght: 322 a.a.
Mass: 35541 Da
fasta formatted sequence

Function: Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
Cellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=In interphase, localizes at both sides of the NPC.

Genetic variants

Database cross-references

UniProt: P55735
Ensembl: ENST00000337354
Ensembl: ENST00000350697
Ensembl: ENST00000397109
MIM: 600152
neXtProt: NX_P55735
Antibodypedia: P55735 (may not find the protein thus also not any antibody)
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