SEC20_HUMAN

Source: PM23856902
BSc_CH
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: BNIP1 , NIP1, SEC20L , TRG8
Protein names and data: SEC20_HUMAN , Vesicle transport protein SEC20 , BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; Transformation-related gene 8 protein; TRG-8 Lenght: 228 a.a.
Mass: 26132 Da
fasta formatted sequence
Function: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy.
Cellular location: Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Tissue specificity: Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.

Genetic variants

Database cross-references

UniProt: Q12981
Ensembl: ENST00000231668
Ensembl: ENST00000351486
Ensembl: ENST00000352523
Ensembl: ENST00000393770
MIM: 603291
neXtProt: NX_Q12981
Antibodypedia: Q12981 (may not find the protein thus also not any antibody)
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