SEMG1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: SEMG1 , SEMG
Protein names and data: SEMG1_HUMAN , Semenogelin-1 , Semenogelin I; SGI; Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein; Flags: Precursor Lenght: 462 a.a.
Mass: 52131 Da
fasta formatted sequence
Function: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.
Cellular location: Secreted.
Tissue specificity: Seminal vesicle.

Genetic variants

Database cross-references

UniProt: P04279
Ensembl: ENST00000244069
Ensembl: ENST00000372781
MIM: 182140
neXtProt: NX_P04279
Antibodypedia: P04279 (may not find the protein thus also not any antibody)
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