SHRM3_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: SHROOM3 , KIAA1481, SHRML , MSTP013
Protein names and data: SHRM3_HUMAN , Protein Shroom3 , Shroom-related protein; hShrmL Lenght: 1996 a.a.
Mass: 216857 Da
fasta formatted sequence

Function: Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity).
Cellular location: Cell junction, adherens junction (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Colocalizes with F-actin in stress fibers and adherens junctions (By similarity).

Genetic variants

Database cross-references

UniProt: Q8TF72
Ensembl: ENST00000296043
MIM: 604570
neXtProt: NX_Q8TF72
Antibodypedia: Q8TF72 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.