SIA8C_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ST8SIA3 , SIAT8C
Protein names and data: SIA8C_HUMAN , Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase; 2.4.99.- , Alpha-2,8-sialyltransferase 8C; Alpha-2,8-sialyltransferase III; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3; Sialyltransferase 8C; SIAT8-C; Sialyltransferase St8Sia III; ST8SiaIII Lenght: 380 a.a.
Mass: 43970 Da
fasta formatted sequence
Function: May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.
Pathway: Protein modification; protein glycosylation.
Cellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Potential).
Tissue specificity: Expressed in fetal and adult brain and fetal liver.

Genetic variants

Database cross-references

UniProt: O43173
Ensembl: ENST00000324000
MIM: 609478
neXtProt: NX_O43173
Antibodypedia: O43173 (may not find the protein thus also not any antibody)
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