RBCC Red Blood Cell Collection

SLK_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: SLK , KIAA0204, STK2
Protein names and data: SLK_HUMAN , STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; 2.7.11.1 , CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2 Lenght: 1235 a.a.
Mass: 142695 Da
fasta formatted sequence
Function: Mediates apoptosis and actin stress fiber dissolution (By similarity).
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.
Cellular location: Cytoplasm (By similarity).
Tissue specificity: Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.

Genetic variants

405 - 405 Q -> K (in a lung adenocarcinoma sample; somatic mutation). VAR_041080
552 - 552 C -> Y (in dbSNP:rs805657). VAR_041081 805657
604 - 604 E -> Q (in an ovarian serous carcinoma sample; somatic mutation). VAR_041082
658 - 658 A -> G (in dbSNP:rs56400929). VAR_041083 56400929
666 - 666 G -> E (in dbSNP:rs7071400). VAR_051666 7071400
679 - 679 I -> T (in dbSNP:rs34326537). VAR_041084 34326537
683 - 683 K -> N (in dbSNP:rs35389916). VAR_041085 35389916
697 - 697 T -> I (in dbSNP:rs3740469). VAR_041086 3740469

Database cross-references

UniProt: Q9H2G2
Ensembl: ENST00000335753
Ensembl: ENST00000369755
neXtProt: NX_Q9H2G2
Antibodypedia: Q9H2G2 (may not find the protein thus also not any antibody)
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