SNP29_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: SNAP29
Protein names and data: SNP29_HUMAN , Synaptosomal-associated protein 29; SNAP-29 , Soluble 29 kDa NSF attachment protein; Vesicle-membrane fusion protein SNAP-29 Lenght: 258 a.a.
Mass: 28970 Da
fasta formatted sequence
Function: SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps.
Disease:
Cellular location: Cytoplasm. Membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic.
Tissue specificity: Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.

Database cross-references

UniProt: O95721
Ensembl: ENST00000215730
MIM: 604202
MIM: 609528
neXtProt: NX_O95721
Antibodypedia: O95721 (may not find the protein thus also not any antibody)
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