SNX2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: SNX2 , TRG9
Protein names and data: SNX2_HUMAN , Sorting nexin-2 , Transformation-related gene 9 protein; TRG-9 Lenght: 519 a.a.
Mass: 58471 Da
fasta formatted sequence

Function: May be involved in several stages of intracellular trafficking. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
Cellular location: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.

Database cross-references

UniProt: O60749
Ensembl: ENST00000379516
MIM: 605929
neXtProt: NX_O60749
Antibodypedia: O60749 (may not find the protein thus also not any antibody)
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