SNX5_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: SNX5
Protein names and data: SNX5_HUMAN , Sorting nexin-5 Lenght: 404 a.a.
Mass: 46816 Da
fasta formatted sequence
Function: May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation.
Cellular location: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle. Note=Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns(3,4)P2). Detected on macropinosomes. Targeted to membrane ruffles in response to EGFR stimulation.

Database cross-references

UniProt: Q9Y5X3
Ensembl: ENST00000377759
Ensembl: ENST00000377768
MIM: 605937
neXtProt: NX_Q9Y5X3
Antibodypedia: Q9Y5X3 (may not find the protein thus also not any antibody)
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