SNX6_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: SNX6
Protein names and data: SNX6_HUMAN , Sorting nexin-6 , TRAF4-associated factor 2; Sorting nexin-6, N-terminally processed Lenght: 406 a.a.
Mass: 46649 Da
fasta formatted sequence
Function: May be involved in several stages of intracellular trafficking. Promotes lysosomal degradation of CDKN1B (By similarity). Plays a role in retrograde protein transport from endosomes to the trans-Golgi network. May function as link between transport vesicles and dynactin. Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network. May contribute to transcription regulation.
Cellular location: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus. Note=Interaction with SNX1 or SNX2 promotes location at endosome membranes. Only a minor proportion is seen in the nucleus.

Database cross-references

UniProt: Q9UNH7
Ensembl: ENST00000396526
Ensembl: ENST00000396534
MIM: 606098
neXtProt: NX_Q9UNH7
Antibodypedia: Q9UNH7 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.