SPE39_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: VIPAS39 , C14orf133, SPE39, VIPAR
Protein names and data: SPE39_HUMAN , Spermatogenesis-defective protein 39 homolog; hSPE-39 , VPS33B-interacting protein in apical-basolateral polarity regulator; VPS33B-interacting protein in polarity and apical restriction Lenght: 493 a.a.
Mass: 57005 Da
fasta formatted sequence
Function: May play a role in vesicular trafficking during spermatogenesis (By similarity). Plays a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes. May play a role in epithelial polarization through stabilization of apical membrane protein content, possibly via the RAB11A-dependent apical recycling pathway. Also involved in direct or indirect transcriptional regulation of E-cadherin.
Disease:
Cellular location: Cytoplasm (By similarity). Cytoplasmic vesicle (By similarity). Early endosome. Recycling endosome. Late endosome. Note=Colocalizes in clusters with VPS33B at cytoplasmic organelles (By similarity).

Database cross-references

UniProt: Q9H9C1
Ensembl: ENST00000327028
Ensembl: ENST00000343765
Ensembl: ENST00000448935
Ensembl: ENST00000553888
Ensembl: ENST00000557658
MIM: 613401
MIM: 613404
neXtProt: NX_Q9H9C1
Antibodypedia: Q9H9C1 (may not find the protein thus also not any antibody)
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