SPEE_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: SRM , SPS1, SRML1
Protein names and data: SPEE_HUMAN , Spermidine synthase; SPDSY; 2.5.1.16 , Putrescine aminopropyltransferase Lenght: 302 a.a.
Mass: 33825 Da
fasta formatted sequence
Function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.
Catalytic activity: S-adenosyl 3-(methylthio)propylamine + putrescine = 5'-S-methyl-5'-thioadenosine + spermidine.
Pathway: Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.

Genetic variants

Database cross-references

UniProt: P19623
Ensembl: ENST00000376957
MIM: 182891
neXtProt: NX_P19623
Antibodypedia: P19623 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.