SPTB2_HUMAN

Source: hRBCD ; ID: IPI00005614
PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: SPTBN1 , SPTB2
Protein names and data: SPTB2_HUMAN , Spectrin beta chain, non-erythrocytic 1 , Beta-II spectrin; Fodrin beta chain; Spectrin, non-erythroid beta chain 1 Lenght: 2364 a.a.
Mass: 274609 Da
fasta formatted sequence
Function: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Cellular location: Cytoplasm, cytoskeleton (By similarity). Cytoplasm, myofibril, sarcomere, M line (By similarity). Note=Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes (By similarity). Isoform 2: Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity).
Tissue specificity: Isoform 2 is present in brain, lung and kidney (at protein level).

Genetic variants

Database cross-references

UniProt: Q01082
Ensembl: ENST00000333896
Ensembl: ENST00000356805
MIM: 182790
neXtProt: NX_Q01082
Antibodypedia: Q01082 (may not find the protein thus also not any antibody)
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