STRAB_HUMAN

Source: PM23856902
BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: STRADB , ALS2CR2, ILPIP , PRO1038
Protein names and data: STRAB_HUMAN , STE20-related kinase adapter protein beta; STRAD beta , Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; CALS-21; ILP-interacting protein; Pseudokinase ALS2CR2 Lenght: 418 a.a.
Mass: 47026 Da
fasta formatted sequence
Function: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
Cellular location: Nucleus. Cytoplasm.
Tissue specificity: Highly expressed in heart, skeletal muscle, testis, liver and colon.

Genetic variants

Database cross-references

UniProt: Q9C0K7
Ensembl: ENST00000194530
Ensembl: ENST00000392249
MIM: 607333
neXtProt: NX_Q9C0K7
Antibodypedia: Q9C0K7 (may not find the protein thus also not any antibody)
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