STRAP_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: STRAP , MAWD, UNRIP
Protein names and data: STRAP_HUMAN , Serine-threonine kinase receptor-associated protein , MAP activator with WD repeats; UNR-interacting protein; WD-40 repeat protein PT-WD Lenght: 350 a.a.
Mass: 38438 Da
fasta formatted sequence
Function: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
Cellular location: Cytoplasm. Nucleus. Note=Localized predominantly in the cytoplasm but also found in the nucleus.

Database cross-references

UniProt: Q9Y3F4
Ensembl: ENST00000419869
MIM: 605986
neXtProt: NX_Q9Y3F4
Antibodypedia: Q9Y3F4 (may not find the protein thus also not any antibody)
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