STX4_HUMAN

Source: hRBCD ; ID: IPI00029730
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: STX4 , STX4A
Protein names and data: STX4_HUMAN , Syntaxin-4 , Renal carcinoma antigen NY-REN-31 Lenght: 297 a.a.
Mass: 34180 Da
fasta formatted sequence
Function: Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
Cellular location: Cell membrane; Single-pass type IV membrane protein (Potential).
Tissue specificity: Expressed in neutrophils and neutrophil- differentiated HL-60 cells. Expression in neutrophils increases with differentiation.

Database cross-references

UniProt: Q12846
Ensembl: ENST00000313843
MIM: 186591
neXtProt: NX_Q12846
Antibodypedia: Q12846 (may not find the protein thus also not any antibody)
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