SYLC_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: LARS , KIAA1352
Protein names and data: SYLC_HUMAN , Leucine--tRNA ligase, cytoplasmic; 6.1.1.4 , Leucyl-tRNA synthetase; LeuRS Lenght: 1176 a.a.
Mass: 134466 Da
fasta formatted sequence
Function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.
Catalytic activity: ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).
Cellular location: Cytoplasm (By similarity).

Genetic variants

Database cross-references

UniProt: Q9P2J5
Ensembl: ENST00000394434
MIM: 151350
neXtProt: NX_Q9P2J5
Antibodypedia: Q9P2J5 (may not find the protein thus also not any antibody)
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