SYNJ1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: SYNJ1 , KIAA0910
Protein names and data: SYNJ1_HUMAN , Synaptojanin-1; 3.1.3.36 , Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1 Lenght: 1573 a.a.
Mass: 173103 Da
fasta formatted sequence
Function: Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis.
Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
Cellular location: Cytoplasm (By similarity).
Tissue specificity: Concentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells. Isoform 2 is very abundant in nerve terminals.

Genetic variants

Database cross-references

UniProt: O43426
Ensembl: ENST00000322229
Ensembl: ENST00000357345
MIM: 604297
neXtProt: NX_O43426
Antibodypedia: O43426 (may not find the protein thus also not any antibody)
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