SYSC_HUMAN

Source: PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: SARS , SERS
Protein names and data: SYSC_HUMAN , Serine--tRNA ligase, cytoplasmic; 6.1.1.11 , Seryl-tRNA synthetase; SerRS; Seryl-tRNA(Ser/Sec) synthetase Lenght: 514 a.a.
Mass: 58777 Da
fasta formatted sequence
Function: Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
Catalytic activity: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).
Pathway: Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
Cellular location: Cytoplasm.

Database cross-references

UniProt: P49591
Ensembl: ENST00000234677
MIM: 607529
neXtProt: NX_P49591
Antibodypedia: P49591 (may not find the protein thus also not any antibody)
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