Source: hRBCD ; ID: IPI00024107
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: SNCA , NACP, PARK1
Protein names and data: SYUA_HUMAN , Alpha-synuclein , Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP Lenght: 140 a.a.
Mass: 14460 Da
fasta formatted sequence

Function: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Cellular location: Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons.
Tissue specificity: Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

Genetic variants

Database cross-references

UniProt: P37840
Ensembl: ENST00000336904
Ensembl: ENST00000345009
Ensembl: ENST00000394986
Ensembl: ENST00000394989
Ensembl: ENST00000394991
Ensembl: ENST00000420646
Ensembl: ENST00000505199
Ensembl: ENST00000506244
Ensembl: ENST00000508895
MIM: 127750
MIM: 163890
MIM: 168600
MIM: 168601
MIM: 605543
neXtProt: NX_P37840
Antibodypedia: P37840 (may not find the protein thus also not any antibody)
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