TBCB_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: TBCB , CG22, CKAP1
Protein names and data: TBCB_HUMAN , Tubulin-folding cofactor B , Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tubulin-specific chaperone B Lenght: 244 a.a.
Mass: 27326 Da
fasta formatted sequence
Function: Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
Cellular location: Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.
Tissue specificity: Found in most tissues.

Database cross-references

UniProt: Q99426
Ensembl: ENST00000221855
MIM: 601303
neXtProt: NX_Q99426
Antibodypedia: Q99426 (may not find the protein thus also not any antibody)
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