TEBP_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: PTGES3 , P23, TEBP
Protein names and data: TEBP_HUMAN , Prostaglandin E synthase 3; 5.3.99.3 , Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23 Lenght: 160 a.a.
Mass: 18697 Da
fasta formatted sequence

Function: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
Catalytic activity: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15- hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11-alpha,15- dihydroxy-9-oxoprosta-5,13-dienoate.
Pathway: Lipid metabolism; prostaglandin biosynthesis.
Cellular location: Cytoplasm.

Database cross-references

UniProt: Q15185
Ensembl: ENST00000262033
MIM: 607061
neXtProt: NX_Q15185
Antibodypedia: Q15185 (may not find the protein thus also not any antibody)
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