RBCC Red Blood Cell Collection

TENS1_HUMAN

Source: PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: TNS1 , TNS
Protein names and data: TENS1_HUMAN , Tensin-1 Lenght: 1735 a.a.
Mass: 185701 Da
fasta formatted sequence
Function: Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.
Cellular location: Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1- dependent manner.
Tissue specificity: Ubiquitous.

Genetic variants

311 - 311 I -> M (in dbSNP:rs11680854). VAR_047066 11680854
466 - 466 R -> C (in dbSNP:rs3815849). VAR_047067 3815849
528 - 528 T -> I (in dbSNP:rs3796033). VAR_047068 3796033
1004 - 1004 R -> W (in dbSNP:rs3796028). VAR_047069 3796028
1093 - 1093 F -> L (in a breast cancer sample; somatic mutation). VAR_048004
1197 - 1197 W -> R (in dbSNP:rs2571445). VAR_047070 2571445
1604 - 1604 V -> I (in dbSNP:rs918949). VAR_047071 918949

Database cross-references

UniProt: Q9HBL0
Ensembl: ENST00000171887
MIM: 600076
neXtProt: NX_Q9HBL0
Antibodypedia: Q9HBL0 (may not find the protein thus also not any antibody)
Local full text data: click here

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