THG1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: THG1L , ICF45
Protein names and data: THG1_HUMAN , Probable tRNA(His) guanylyltransferase; 2.7.7.79 , Interphase cytoplasmic foci protein 45; tRNA-histidine guanylyltransferase Lenght: 298 a.a.
Mass: 34831 Da
fasta formatted sequence
Function: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.
Catalytic activity: p-tRNA(His) + ATP + GTP = pppG-P-tRNA(His) + AMP + diphosphate.
Cellular location: Cytoplasm. Note=Found near the nuclear membrane.
Tissue specificity: Expressed in many tissues.

Genetic variants

Database cross-references

UniProt: Q9NWX6
Ensembl: ENST00000231198
neXtProt: NX_Q9NWX6
Antibodypedia: Q9NWX6 (may not find the protein thus also not any antibody)
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