TLE3_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: TLE3 , KIAA1547
Protein names and data: TLE3_HUMAN , Transducin-like enhancer protein 3 , Enhancer of split groucho-like protein 3; ESG3 Lenght: 772 a.a.
Mass: 83417 Da
fasta formatted sequence

Function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Cellular location: Nucleus.
Tissue specificity: Placenta and lung.

Genetic variants

Database cross-references

UniProt: Q04726
Ensembl: ENST00000317509
Ensembl: ENST00000451782
Ensembl: ENST00000557907
Ensembl: ENST00000557997
Ensembl: ENST00000558939
Ensembl: ENST00000559048
MIM: 600190
neXtProt: NX_Q04726
Antibodypedia: Q04726 (may not find the protein thus also not any antibody)
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