Source: PM19886704
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: TLN1 , KIAA1027, TLN
Protein names and data: TLN1_HUMAN , Talin-1 Lenght: 2541 a.a.
Mass: 269767 Da
fasta formatted sequence

Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity).
Cellular location: Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasm, cytoskeleton (By similarity). Cell surface (By similarity). Cell junction, focal adhesion (By similarity). Note=Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).

Genetic variants

Database cross-references

UniProt: Q9Y490
Ensembl: ENST00000314888
MIM: 186745
neXtProt: NX_Q9Y490
Antibodypedia: Q9Y490 (may not find the protein thus also not any antibody)
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