RBCC Red Blood Cell Collection

TLN2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: TLN2 , KIAA0320
Protein names and data: TLN2_HUMAN , Talin-2 Lenght: 2542 a.a.
Mass: 271613 Da
fasta formatted sequence
Function: As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).
Cellular location: Cell junction, focal adhesion. Cell junction, synapse. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Focal adhesion plaques and synapses.

Genetic variants

340 - 340 V -> A (in dbSNP:rs11634784). VAR_055313 11634784
1148 - 1148 A -> S (in dbSNP:rs2280279). VAR_014432 2280279
1148 - 1148 A -> T (in dbSNP:rs2280279). VAR_059136 2280279
1877 - 1877 V -> I (in dbSNP:rs7182971). VAR_055314 7182971
2144 - 2144 T -> I (in dbSNP:rs11633796). VAR_055315 11633796
2266 - 2266 F -> L (in dbSNP:rs3816988). VAR_014433 3816988

Database cross-references

UniProt: Q9Y4G6
Ensembl: ENST00000306829
Ensembl: ENST00000561311
MIM: 607349
neXtProt: NX_Q9Y4G6
Antibodypedia: Q9Y4G6 (may not find the protein thus also not any antibody)
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