TMOD1_HUMAN

Source: hRBCD ; ID: IPI00002375
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: TMOD1 , D9S57E, TMOD
Protein names and data: TMOD1_HUMAN , Tropomodulin-1 , Erythrocyte tropomodulin; E-Tmod Lenght: 359 a.a.
Mass: 40569 Da
fasta formatted sequence
Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Cellular location: Cytoplasm, cytoskeleton.
Tissue specificity: Highly expressed in the erythrocyte, heart and skeletal muscle.

Database cross-references

UniProt: P28289
Ensembl: ENST00000259365
Ensembl: ENST00000395211
MIM: 190930
neXtProt: NX_P28289
Antibodypedia: P28289 (may not find the protein thus also not any antibody)
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