TP4A1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PTP4A1 , PRL1, PTPCAAX1
Protein names and data: TP4A1_HUMAN , Protein tyrosine phosphatase type IVA 1; 3.1.3.48 , PTP(CAAXI); Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PRL-1; Flags: Precursor Lenght: 173 a.a.
Mass: 19815 Da
fasta formatted sequence
Function: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.
Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
Cellular location: Cell membrane. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=And mitotic spindle.
Tissue specificity: Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines.

Database cross-references

UniProt: Q93096
Ensembl: ENST00000370651
MIM: 601585
neXtProt: NX_Q93096
Antibodypedia: Q93096 (may not find the protein thus also not any antibody)
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