Source: hRBCD ; ID: IPI00218319
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: TPM3
Protein names and data: TPM3_HUMAN , Tropomyosin alpha-3 chain , Gamma-tropomyosin; Tropomyosin-3; Tropomyosin-5; hTM5 Lenght: 285 a.a.
Mass: 32950 Da
fasta formatted sequence

Function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Cellular location: Cytoplasm, cytoskeleton.

Genetic variants

Database cross-references

UniProt: P06753
Ensembl: ENST00000323144
Ensembl: ENST00000330188
Ensembl: ENST00000368530
Ensembl: ENST00000368531
Ensembl: ENST00000368533
MIM: 164970
MIM: 188550
MIM: 191030
MIM: 255310
MIM: 609284
neXtProt: NX_P06753
Antibodypedia: P06753 (may not find the protein thus also not any antibody)
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