TPRKB_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: TPRKB , CGI-121, My019
Protein names and data: TPRKB_HUMAN , EKC/KEOPS complex subunit TPRKB , PRPK-binding protein; TP53RK-binding protein Lenght: 175 a.a.
Mass: 19661 Da
fasta formatted sequence
Function: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (By similarity).
Cellular location: Cytoplasm. Nucleus.
Tissue specificity: Widely expressed.

Database cross-references

UniProt: Q9Y3C4
Ensembl: ENST00000272424
Ensembl: ENST00000318190
Ensembl: ENST00000409716
MIM: 608680
neXtProt: NX_Q9Y3C4
Antibodypedia: Q9Y3C4 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.