TPSN_HUMAN

Source: BSc_CH
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: TAPBP , NGS17, TAPA
Protein names and data: TPSN_HUMAN , Tapasin; TPN; TPSN , NGS-17; TAP-associated protein; TAP-binding protein; Flags: Precursor Lenght: 448 a.a.
Mass: 47626 Da
fasta formatted sequence
Function: Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
Cellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein (Probable).
Tissue specificity: Neutrophils, mostly in fully differentiated cells.

Genetic variants

The 2 alleles of TAPBP; TAPBP*01 (Tapasin*01) (shown here) and TAPBP*02 (Tapasin*02); are in linkage disequilibria with the HLA-DRB1 locus in a Japanese population.

Database cross-references

UniProt: O15533
Ensembl: ENST00000374572
Ensembl: ENST00000383066
Ensembl: ENST00000383197
Ensembl: ENST00000383198
Ensembl: ENST00000395114
Ensembl: ENST00000417059
Ensembl: ENST00000434618
Ensembl: ENST00000456807
MIM: 601962
neXtProt: NX_O15533
Antibodypedia: O15533 (may not find the protein thus also not any antibody)
Local full text data: click here

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