TRAD1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: TRAFD1 , FLN29
Protein names and data: TRAD1_HUMAN , TRAF-type zinc finger domain-containing protein 1 , Protein FLN29 Lenght: 582 a.a.
Mass: 64841 Da
fasta formatted sequence
Function: Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).

Database cross-references

UniProt: O14545
Ensembl: ENST00000257604
Ensembl: ENST00000412615
MIM: 613197
neXtProt: NX_O14545
Antibodypedia: O14545 (may not find the protein thus also not any antibody)
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