TRAK1_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: TRAK1 , KIAA1042, OIP106
Protein names and data: TRAK1_HUMAN , Trafficking kinesin-binding protein 1 , 106 kDa O-GlcNAc transferase-interacting protein Lenght: 953 a.a.
Mass: 106040 Da
fasta formatted sequence

Function: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors.
Cellular location: Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Note=Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HRS. Colocalizes with MGARP at the mitochondria.
Tissue specificity: High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.

Database cross-references

UniProt: Q9UPV9
Ensembl: ENST00000327628
Ensembl: ENST00000449246
MIM: 608112
neXtProt: NX_Q9UPV9
Antibodypedia: Q9UPV9 (may not find the protein thus also not any antibody)
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