TRI56_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: TRIM56 , RNF109
Protein names and data: TRI56_HUMAN , E3 ubiquitin-protein ligase TRIM56; 6.3.2.- , RING finger protein 109; Tripartite motif-containing protein 56 Lenght: 755 a.a.
Mass: 81488 Da
fasta formatted sequence
Function: E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA (By similarity).
Cellular location: Cytoplasm (By similarity).

Database cross-references

UniProt: Q9BRZ2
Ensembl: ENST00000306085
neXtProt: NX_Q9BRZ2
Antibodypedia: Q9BRZ2 (may not find the protein thus also not any antibody)
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