TWF2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: TWF2 , PTK9L , MSTP011
Protein names and data: TWF2_HUMAN , Twinfilin-2 , A6-related protein; hA6RP; Protein tyrosine kinase 9-like; Twinfilin-1-like protein Lenght: 349 a.a.
Mass: 39548 Da
fasta formatted sequence
Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity).
Cellular location: Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium (By similarity). Note=Perinuclear and G-actin-rich cortical actin structure sublocalization.
Tissue specificity: Ubiquitously expressed (at protein level).

Genetic variants

Database cross-references

UniProt: Q6IBS0
Ensembl: ENST00000305533
MIM: 607433
neXtProt: NX_Q6IBS0
Antibodypedia: Q6IBS0 (may not find the protein thus also not any antibody)
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