UBAP1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: UBAP1 , NAG20
Protein names and data: UBAP1_HUMAN , Ubiquitin-associated protein 1; UBAP-1 , Nasopharyngeal carcinoma-associated gene 20 protein Lenght: 502 a.a.
Mass: 55084 Da
fasta formatted sequence
Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2.
Cellular location: Cytoplasm, cytosol. Endosome. Note=Predominantly cytosolic. Recruited to endosomes as part of the ESCRT-I complex.
Tissue specificity: Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.

Genetic variants

Database cross-references

UniProt: Q9NZ09
Ensembl: ENST00000297661
Ensembl: ENST00000359544
Ensembl: ENST00000379186
Ensembl: ENST00000536252
Ensembl: ENST00000540348
Ensembl: ENST00000543944
Ensembl: ENST00000545103
MIM: 609787
neXtProt: NX_Q9NZ09
Antibodypedia: Q9NZ09 (may not find the protein thus also not any antibody)
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