UDB28_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: UGT2B28
Protein names and data: UDB28_HUMAN , UDP-glucuronosyltransferase 2B28; UDPGT 2B28; 2.4.1.17; Flags: Precursor Lenght: 529 a.a.
Mass: 60906 Da
fasta formatted sequence
Function: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta- diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active.
Catalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
Cellular location: Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue specificity: Expressed in the liver, breast and kidney.

Genetic variants

Database cross-references

UniProt: Q9BY64
Ensembl: ENST00000335568
Ensembl: ENST00000511240
MIM: 606497
neXtProt: NX_Q9BY64
Antibodypedia: Q9BY64 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.