UGGG1_HUMAN

Source: PM19886704
BSc_CH
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: UGGT1 , GT, UGCGL1, UGGT, UGT1, UGTR
Protein names and data: UGGG1_HUMAN , UDP-glucose:glycoprotein glucosyltransferase 1; UGT1; hUGT1; 2.4.1.- , UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; Flags: Precursor Lenght: 1555 a.a.
Mass: 177190 Da
fasta formatted sequence
Function: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Pathway: Protein modification; protein glycosylation.
Cellular location: Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
Tissue specificity: Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.

Database cross-references

UniProt: Q9NYU2
Ensembl: ENST00000259253
Ensembl: ENST00000375990
MIM: 605897
neXtProt: NX_Q9NYU2
Antibodypedia: Q9NYU2 (may not find the protein thus also not any antibody)
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