Source: hRBCD ; ID: IPI00006211
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: VAPB , UNQ484/PRO983
Protein names and data: VAPB_HUMAN , Vesicle-associated membrane protein-associated protein B/C; VAMP-B/VAMP-C; VAMP-associated protein B/C; VAP-B/VAP-C Lenght: 243 a.a.
Mass: 27228 Da
fasta formatted sequence

Function: Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
Cellular location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity). Note=Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane.
Tissue specificity: Ubiquitous. Isoform 1 predominates.

Genetic variants

Database cross-references

UniProt: O95292
Ensembl: ENST00000395802
Ensembl: ENST00000475243
MIM: 182980
MIM: 605704
MIM: 608627
neXtProt: NX_O95292
Antibodypedia: O95292 (may not find the protein thus also not any antibody)
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