VDAC2_HUMAN

Source: BSc_CH
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: VDAC2
Protein names and data: VDAC2_HUMAN , Voltage-dependent anion-selective channel protein 2; VDAC-2; hVDAC2 , Outer mitochondrial membrane protein porin 2 Lenght: 294 a.a.
Mass: 31567 Da
fasta formatted sequence

Function: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective.
Cellular location: Mitochondrion outer membrane.
Tissue specificity: Expressed in all tissues examined.

Genetic variants

Database cross-references

UniProt: P45880
Ensembl: ENST00000313132
Ensembl: ENST00000332211
Ensembl: ENST00000543351
MIM: 193245
neXtProt: NX_P45880
Antibodypedia: P45880 (may not find the protein thus also not any antibody)
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