VP33B_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: VPS33B
Protein names and data: VP33B_HUMAN , Vacuolar protein sorting-associated protein 33B; hVPS33B Lenght: 617 a.a.
Mass: 70585 Da
fasta formatted sequence

Function: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages.
Disease:
Cellular location: Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes. Colocalizes with M.tuberculosis PtpA in the cytosol of tuberculosis-infected macrophages and associates with phagosomes. Colocalizes in clusters with VIPAS39 at cytoplasmic organelles.
Tissue specificity: Ubiquitous; highly expressed in testis and low expression in the lung.

Genetic variants

Database cross-references

UniProt: Q9H267
Ensembl: ENST00000333371
MIM: 208085
MIM: 608552
neXtProt: NX_Q9H267
Antibodypedia: Q9H267 (may not find the protein thus also not any antibody)
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