VPP4_HUMAN

Source: PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: ATP6V0A4 , ATP6N1B, ATP6N2
Protein names and data: VPP4_HUMAN , V-type proton ATPase 116 kDa subunit a isoform 4; V-ATPase 116 kDa isoform a4 , Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4; Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform Lenght: 840 a.a.
Mass: 96386 Da
fasta formatted sequence

Function: Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity).
Disease:
Cellular location: Apical cell membrane; Multi-pass membrane protein. Note=Present at high density almost exclusively on the apical surface of alpha-intercalated cells in the cortical collecting ducts of the distal nephron.
Tissue specificity: Expressed in adult and fetal kidney. Found in the inner ear.

Genetic variants

Database cross-references

UniProt: Q9HBG4
Ensembl: ENST00000310018
Ensembl: ENST00000353492
Ensembl: ENST00000393054
MIM: 602722
MIM: 605239
neXtProt: NX_Q9HBG4
Antibodypedia: Q9HBG4 (may not find the protein thus also not any antibody)
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